科学研究

1. Zinzula L. (2023). Ebolavirus VP40 redux. Or rather, redox. Structure (London, England: 1993), 31(9), 1008–1010.

2. Liu, R., Qi, J., Wang, H., Fan, L., Zhang, P., Yu, J., Tan, L., Wang, S., & Cheng, J. (2023). Transformation of a Dopamine D2 Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents. Journal of medicinal chemistry, 66(9), 6274–6287. 

3. Duan, W., Cao, D., Wang, S., & Cheng, J. (2023). Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants. Chemical reviews, 10.1021/acs.chemrev.3c00375. Advance online publication. 

4. Zhang, J., Feng, D., Cheng, J., & Wüthrich, K. (2023). Adenosine A2A Receptor (A2AAR) Ligand Screening Using the 19F-NMR Probe FPPA. Journal of the American Chemical Society, 145(28), 15061–15064. 

5. Mao, J., Cui, Y., Wang, H., Duan, W., Liu, Z. J., Hua, T., Zhou, N., & Cheng, J. (2023). Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction and Cognitive Impairment. Journal of medicinal chemistry, 66(20), 14011–14028. 

6. Wang, D., Li, H., Xu, M., Bo, B., Pei, M., Liang, Z., & Thompson, G. J. (2023). Differential Effect of Global Signal Regression Between Awake and Anesthetized Conditions in Mice. Brain connectivity, 10.1089/brain.2023.0032. Advance online publication. 

7. Wang, Y., Wu, L., Wang, T., Liu, J., Li, F., Jiang, L., Fan, Z., Yu, Y., Chen, N., Sun, Q., Tan, Q., Hua, T., & Liu, Z. J. (2023). Cryo-EM structure of cannabinoid receptor CB1-β-arrestin complex. Protein & cell, pwad055. Advance online publication. 

8. Yang, Y., Kang, H. J., Gao, R., Wang, J., Han, G. W., DiBerto, J. F., Wu, L., Tong, J., Qu, L., Wu, Y., Pileski, R., Li, X., Zhang, X. C., Zhao, S., Kenakin, T., Wang, Q., Stevens, R. C., Peng, W., Roth, B. L., Rao, Z., Liu, Z. J. (2023). Structural insights into the human niacin receptor HCA2-Gi signalling complex. Nature communications, 14(1), 1692. 

9. Li, X., Chang, H., Bouma, J., de Paus, L. V., Mukhopadhyay, P., Paloczi, J., Mustafa, M., van der Horst, C., Kumar, S. S., Wu, L., Yu, Y., van den Berg, R. J. B. H. N., Janssen, A. P. A., Lichtman, A., Liu, Z. J., Pacher, P., van der Stelt, M., Heitman, L. H., & Hua, T. (2023). Structural basis of selective cannabinoid CB2 receptor activation. Nature communications, 14(1), 1447. 

10.   Li, H., Zhang, J., Yu, Y., Luo, F., Wu, L., Liu, J., Chen, N., Liu, Z., & Hua, T. (2023). Structural insight into the constitutive activity of human orphan receptor GPR12. Science bulletin, 68(1), 95–104. 

11.   Pan, C., Li, J., Yuan, S., & Shui, W. (2022). Probing the structures of G protein-coupled receptors with mass spectrometry-based techniques. International Journal of Mass Spectrometry. 

12.   Xin, Y., Liu, S., Liu, Y., Qian, Z., Liu, H., Zhang, B., Guo, T., Thompson, G. J., Stevens, R. C., Sharpless, K. B., Dong, J., & Shui, W. (2023). Affinity selection of double-click triazole libraries for rapid discovery of allosteric modulators for GLP-1 receptor. Proceedings of the National Academy of Sciences of the United States of America, 120(11), e2220767120. 

13.   Yuan, S., Xia, L., Wang, C., Wu, F., Zhang, B., Pan, C., Fan, Z., Lei, X., Stevens, R. C., Sali, A., Sun, L., & Shui, W. (2023). Conformational Dynamics of the Activated GLP-1 Receptor-Gs Complex Revealed by Cross-Linking Mass Spectrometry and Integrative Structure Modeling. ACS central science, 9(5), 992–1007. 

14.   Lou, R., Cao, Y., Li, S., Lang, X., Li, Y., Zhang, Y., & Shui, W. (2023). Benchmarking commonly used software suites and analysis workflows for DIA proteomics and phosphoproteomics. Nature communications, 14(1), 94. 

15.   Wan, W., Qin, Q., Xie, L., Zhang, H., Wu, F., Stevens, R. C., & Liu, Y. (2023). GLP-1R Signaling and Functional Molecules in Incretin Therapy. Molecules (Basel, Switzerland), 28(2), 751. 

16.   Wang, H., Hu, W., Xu, T., Yuan, Y., Liu, D., & Wüthrich, K. (2023). Selective polypeptide ligand binding to the extracellular surface of the transmembrane domains of the class B GPCRs GLP-1R and GCGR. iScience, 26(6), 106918. 

17.   Feng, D., Feng, G., Song, Y., & Wüthrich, K. (2023). Solvent accessibility of a GPCR transmembrane domain probed by in-membrane chemical modification (IMCM). FEBS letters, 597(11), 1541–1549. 

18.   Lin, X., Chen, B., Wu, Y., Han, Y., Qi, A., Wang, J., Yang, Z., Wei, X., Zhao, T., Wu, L., Xie, X., Sun, J., Zheng, J., Zhao, S., & Xu, F. (2023). Cryo-EM structures of orphan GPR21 signaling complexes. Nature communications, 14(1), 216. 

19.   Lin, X., Jiang, S., Wu, Y., Wei, X., Han, G. W., Wu, L., Liu, J., Chen, B., Zhang, Z., Zhao, S., Cherezov, V., & Xu, F. (2023). The activation mechanism and antibody binding mode for orphan GPR20. Cell discovery, 9(1), 23.

20.   Zhang, Z., Lin, X., Wei, L., Wu, Y., Xu, L., Wu, L., Wei, X., Wang, A., Zhao, S., Zhu, X., & Xu, F. (2023). A framework for Frizzled-G protein coupling and implications to the Wnt-PCP signaling pathways. bioRxiv.

21.   Chen, Y., Chen, B., Wu, T., Zhou, F., & Xu, F. (2023). Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A. Protein & cell, 14(6), 464–468. 

22.   Li, C., Wu, Y., Wang, W., Xu, L., Zhou, Y., Yue, Y., Wu, T., Yang, M., Qiu, Y., Huang, M., Zhou, F., Zhou, Y., Hao, P., Lin, Z., Wang, M. W., Zhao, S., Yang, D., Xu, F., & Tao, H. (2023). Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. Journal of medicinal chemistry, 66(17), 11855–11868. 

23.   Guo, Y., Zhou, Q., Wei, B., Wang, M. W., & Zhao, S. (2023). GPCRana: A web server for quantitative analysis of GPCR structures. Structure (London, England : 1993), 31(9), 1132–1142.e2. 

24.   陈荟玉 & 赵素文.(2023).噬菌体Z基因组生物合成通路的研究进展. 遗传(10),887-903. 

25.   Zhao, S., Liu, F., Qiu, S., Lan, Q., Wu, Y., Xu, W., Ke, J., Yang, J., Liu, X., Wang, K., Guo, H., Xia, S., Zhang, F., Wang, J., Hu, X., Lu, L., Jiang, S., Zhao, S., Liu, L., Xie, Y., Yang, X., Wang, H., Zhong, G. (2022). A core epitope targeting antibody of SARS-CoV-2. Protein & cell, 14(1), 74–78. 

26.   Yang, Y., Wang, Q., Mei, B., Han, Z., Sun, F., Shang, L., Yang, S., Wei, Y., Wu, D., & Jiang, Z. (2023). Theory‐guided Design of Atomically Dispersed Dual‐Metal Catalysts for Superior Oxygen Reduction Reaction Activity. ChemCatChem, 15.

27.   Lu, C., Zhu, X., Feng, Y., Ao, W., Li, J., Gao, Z., Luo, H., Chen, M., Cai, F., Zhan, S., Li, H., Sun, W., & Hu, J. (2023). Atypical antipsychotics antagonize GABAA receptors in the ventral tegmental area GABA neurons to relieve psychotic behaviors. Molecular psychiatry, 28(5), 2107–2121. 

28.   Li, J., Guan, X., Wu, Q., He, C., Zhang, W., Lin, X., Liu, C., Wei, H., Xu, X., & Zhang, Y. (2023). Direct localization and delineation of human pedunculopontine nucleus based on a self-supervised magnetic resonance image super-resolution method. Human brain mapping, 44(9), 3781–3794.

29.   Wu, Q., Feng, R., Wei, H., Yu, J., & Zhang, Y. (2022). Self-Supervised Coordinate Projection Network for Sparse-View Computed Tomography. IEEE Transactions on Computational Imaging, 9, 517-529.

30.   Wang, T., Shi, S., Shi, Y., Jiang, P., Hu, G., Ye, Q., Shi, Z., Yu, K., Wang, C., Fan, G., Zhao, S., Ma, H., Chang, A. C. Y., Li, Z., Bian, Q., & Lin, C. P. (2023). Chemical-induced phase transition and global conformational reorganization of chromatin. Nature communications, 14(1), 5556. 

31.   Chen, S., Wu, Y., Gao, Y., Wu, C., Wang, Y., Hou, C., Ren, M., Zhang, S., Zhu, Q., Zhang, J., Yao, Y., Huang, M., Qi, Y. B., Liu, X. S., Horng, T., Wang, H., Ye, D., Zhu, Z., Zhao, S., & Fan, G. (2023). Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness. Cell reports, 42(10), 113246. 

32.   Zhu, X., Gu, L., Li, R., Chen, L., Chen, J., Zhou, N., & Ren, W. (2023). MiniMounter: A low-cost miniaturized microscopy development toolkit for image quality control and enhancement. Journal of biophotonics, e202300214. Advance online publication. 

33.   Boniardi, I., Corona, A., Basquin, J., Basquin, C., Milia, J., Nagy, I., Tramontano, E., & Zinzula, L.(2023). Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function. Virus research, 336, 199221. 

34.   Sun, N., Yang, K., Yan, W., Yao, M., Yu, C., Duan, W., Gu, X., Guo, D., Jiang, H., Xie, C., &Cheng, J. (2023). Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response. Journal of medicinal chemistry, 66(7), 4802–4826. 

35.   Maccarrone, M., Di Marzo, V., Gertsch, J., Grether, U., Howlett, A. C., Hua, T., Makriyannis, A., Piomelli, D., Ueda, N., & van der Stelt, M. (2023). Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years. Pharmacological reviews, 75(5), 885–958.

36.   Xie, F., Xie, M., Yang, Y., Ao, W., Zhao, T., Liu, N., Chen, B., Kang, W., Xiao, W., & Gu, J. (2023). Pathway network-based quantitative modeling of the time-dependent and dose-response anti-inflammatory effect of Reduning Injection. Journal of ethnopharmacology, 307, 116216. 

37.   Sun, M., Liu, M., Shan, H., Li, K., Wang, P., Guo, H., Zhao, Y., Wang, R., Tao, Y., Yang, L., Zhang, Y., Su, X., Liu, Y., Li, C., Lin, J., Chen, X. L., Zhang, Y. Z., & Shen, Q. T. (2023). Ring-stacked capsids of white spot syndrome virus and structural transitions with genome ejection. Science advances, 9(8), eadd2796. 

38.   Sugiyama, Y., & Aoki, Y. (2023). A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept. Drug metabolism and disposition: the biological fate of chemicals, 51(9), 1067–1076. 

39.   Aoki, Y., & Sugiyama, Y. (2023). Cluster Gauss-Newton method for a quick approximation of profile likelihood: With application to physiologically-based pharmacokinetic models. CPT: pharmacometrics & systems pharmacology, 10.1002/psp4.13055. Advance online publication. 

40.   de Arce, K. P., Ribic, A., Chowdhury, D., Watters, K., Thompson, G. J., Sanganahalli, B. G., Lippard, E. T. C., Rohlmann, A., Strittmatter, S. M., Missler, M., Hyder, F., & Biederer, T. (2023). Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions. Nature communications, 14(1), 459. 

41.   Dou, W. T., Qiu, P., Shi, Y., Zhu, L., Guo, C., Li, N., Zang, Y., Liu, T., Zhao, S., Pan, Y., Dong, L., Sessler, J. L., Tan, Y., Li, J., Wang, H., Tian, H., & He, X. P. (2023). Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer. Journal of the American Chemical Society, 145(31), 17377–17388. 

42.   Tong, Y., Wu, X., Liu, Y., Chen, H., Zhou, Y., Jiang, L., Li, M., Zhao, S., & Zhang, Y. (2023). Alternative Z-genome biosynthesis pathway shows evolutionary progression from Archaea to phage. Nature microbiology, 8(7), 1330–1338. 

43.   Wang, Y., Chi, Z., Jia, S., Zhao, S., Cao, G., Purev, C., Cang, M., Yu, H., Li, X., Bao, S., Liu, Y., Wang, J., & Tong, B. (2023). Effects of novel variants in BMP15 gene on litter size in Mongolia and Ujimqin sheep breeds. Theriogenology, 198, 1–11. 

44.   Qiu, Y., Zhao, Y., Hu, T., Yang, M., Li, F., Li, C., Gu, W., Yang, X., Zhao, S., & Tao, H. (2023). Development of Yin-Yang ligand for cannabinoid receptors. Bioorganic chemistry, 133, 106377. 

45.   韩伟,赵素文,黄行许 林峰.(2023).脊索动物嗅觉受体基因命名法的发展.生命的化学(05),648-656.

46.   Fan, S., Yan, Y., Xia, Y., Zhou, Z., Luo, L., Zhu, M., Han, Y., Yao, D., Zhang, L., Fang, M., Peng, L., Yu, J., Liu, Y., Gao, X., Guan, H., Li, H., Wang, C., Wu, X., Zhu, H., Cao, Y., Huang, C. (2023). Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions. Nature communications, 14(1), 3368. 

47.   Shi, X., Chen, S., Li, S., Yang, Y., Guan, Q., Ding, J., Liu, X., Liu, Q., Xu, W., & Lu, J. (2023). Particle size effect of SiO2-supported ZnO catalysts in propane dehydrogenation. Catalysis Science & Technology.

48.   Mendoza-Hoffmann, F., Yang, L., Buratto, D., Brito-Sánchez, J., Garduño-Javier, G., Salinas-López, E., Uribe-Álvarez, C., Ortega, R., Sotelo-Serrano, O., Cevallos, M. Á., Ramírez-Silva, L., Uribe-Carvajal, S., Pérez-Hernández, G., Celis-Sandoval, H., & García-Trejo, J. J. (2023). Inhibitory to non-inhibitory evolution of the ζ subunit of the F1FO-ATPase of Paracoccus denitrificans and α-proteobacteria as related to mitochondrial endosymbiosis. Frontiers in molecular biosciences, 10, 1184200. 

49.   Yingsu, J., Liu, Y., Huang, H., Yang, L., Qian, Y., Fu, X., & Liu, H. (2023). Molten-Salt Synthesis of Triazine-Based Carbon Nitride and Its Photocatalytic Degradation Mechanism Investigation by In Situ NMR. The Journal of Physical Chemistry C.

50.   Liu, H., Zheng, Y., Wang, Y., Wang, Y., He, X., Xu, P., Huang, S., Yuan, Q., Zhang, X., Wang, L., Jiang, K., Chen, H., Li, Z., Liu, W., Wang, S., Xu, H. E., & Xu, F. (2023). Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624(7992), 663–671.