科学研究

1.     

Zhang, X.Stevens, R.C., and Xu, F. (2015). The importance of ligands for G protein-coupled receptor stability. Trends in Biochemical Sciences 40, 79-87.

2.     

Kang, Y., Zhou, X.E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., Sathish, D., Yefanov, O., Han, G.W., Xu, Q., de Waal, P.W., Ke, J., Tan, M.H.E., Zhang, C., Moeller, A., West, G.M., Pascal, B.D., Van Eps, N., Caro, L.N., Vishnivetskiy, S.A., Lee, R.J., Suino-Powell, K.M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G.J., Messerschmidt, M., Gati, C., Zatsepin, N.A., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C.E., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C.S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Ernst, O.P., Katritch, V., Gurevich, V.V., Griffin, P.R., Hubbell, W.L., Stevens, R.C., Cherezov, V., Melcher, K., and Xu, H.E. (2015). Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 523, 561.

3.     

Zhang, D., Gao, Z., Zhang, K., Kiselev, E., Crane, S., Wang, J., Paoletta, S., Yi, C., Ma, L., Zhang, W., Han, G.W., Liu, H., Cherezov, V., Katritch, V., Jiang, H., Stevens, R.C., Jacobson, K.A., Zhao, Q., and Wu, B. (2015). Two disparate ligand-binding sites in the human P2Y(1) receptor. Nature 520, 317.

4.     

Chrencik, Jill E., Roth, Christopher B., Terakado, M., Kurata, H., Omi, R., Kihara, Y., Warshaviak, D., Nakade, S., Asmar-Rovira, G., Mileni, M., Mizuno, H., Griffith, Mark T., Rodgers, C., Han, Gye W., Velasquez, J., Chun, J., Stevens, Raymond C., and Hanson, Michael A. (2015). Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell 161, 1633-1643.

5.     

Zhang, H., Unal, H., Gati, C., Han, Gye W., Liu, W., Zatsepin, Nadia A., James, D., Wang, D., Nelson, G., Weierstall, U., Sawaya, Michael R., Xu, Q., Messerschmidt, M., Williams, Garth J., Boutet, S., Yefanov, Oleksandr M., White, Thomas A., Wang, C., Ishchenko, A., Tirupula, Kalyan C., Desnoyer, R., Coe, J., Conrad, Chelsie E., Fromme, P., Stevens, Raymond C., Katritch, V., Karnik, Sadashiva S., and Cherezov, V. (2015). Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography. Cell 161, 833-844.

6.     

Yang, L., Yang, D., de Graaf, C., Moeller, A., West, G.M., Dharmarajan, V., Wang, C., Siu, F.Y., Song, G., Reedtz-Runge, S., Pascal, B.D., Wu, B., Potter, C.S., Zhou, H., Griffin, P.R., Carragher, B., Yang, H., Wang, M.-W., Stevens, R.C., and Jiang, H. (2015). Conformational states of the full-length glucagon receptor. Nature Communications 6, 7859.