The Smart Imaging Core of the iHuman Institute at ShanghaiTech University is built upon advanced super-resolution microscopy and continuously expands capabilities in the development of novel molecular probes for real-time monitoring of target dynamics and functional states. In parallel, the Core develops artificial intelligence methods and algorithms for target tracking and data analysis, providing comprehensive support for frontier research in basic science and translational medicine.
The Core is equipped with a comprehensive suite of imaging and experimental infrastructure, including six large-scale microscopy systems, an electrophysiology platform, a cryo-microtome, a vibratome, and high-performance computing servers. These facilities enable integrated, end-to-end technical services covering cell and tissue sample preparation, image acquisition, and data analysis.
The Core’s primary services and technical directions include:
1. Super-resolution microscopy and multi-scale live-cell imaging;
2. Two-photon microscopy imaging;
3. Development of novel molecular probes for real-time monitoring of target dynamics and function;
4. Development of artificial intelligence–based methods and algorithms for target tracking and data analysis;
5. Participation in photon-counting CT imaging research, promoting the deep integration of microscopy with medical imaging modalities such as CT and fMRI, and advancing the development of an integrated multimodal imaging framework.
Femtonics Two-Photon Microscope
Nikon CSU-W1 SoRa Spinning Disk Super Resolution Microscope
Patch Clamp Recording System
Super-Resolution Microscope (STORM, STED, SIM)