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Research
Featured Publication
Featured Publication
Bitter taste TAS2R14 activation by intracellular tastants and cholesterol
NATURE, 22 MAY, 2024
2024-05-23
Flexible scaffold-based cheminformatics approach for polypharmacological drug design
CELL, 28 MARCH, 2024
2024-03-28
Recognition of methamphetamine and other amines by trace amine receptor TAAR1
NATURE, 7 NOVEMBER, 2023
2023-11-08
Structural basis for strychnine activation of human bitter taste receptor TAS2R46
SCIENCE, 16 SEPTEMBER, 2022
2022-09-16
Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1
NATURE, 13 APRIL, 2022
2022-07-06
Structure-based discovery of nonhallucinogenic psychedelic analogs
SCIENCE, 28 JANUARY, 2022
2022-01-28
A widespread pathway for substitution of adenine by diaminopurine in phage genomes
SCIENCE, 30 APRIL, 2021
2021-05-25
Structural basis of CXC chemokine receptor 2 activation and signalling
NATURE, 1 JULY, 2020
2020-07-01
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand
SCIENCE, 24 APRIL, 2020
2020-04-26
Structural basis of ligand recognition and self-activation of orphan GPR52
NATURE, 20 FEBRUARY, 2020
2020-03-17
Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures
CELL, 30 JANUARY, 2020
2020-03-11
Crystal Structure of the Human Cannabinoid Receptor CB2
CELL, 24 JANUARY, 2019
2019-03-27
Crystal structure of the Frizzled 4 receptor in a ligand-free state
NATURE, 22 AUGUST, 2018
2018-09-03
Crystal Structure of the Human Cannabinoid Receptor CB1
CELL, 20 OCTOBER, 2016
2018-07-31
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