Oxygen to Glucose Index (OGI) as a biomarker for epileptogenic focus

为了更好地了解癫痫的代谢特征，我们开发了一种单次测量氧葡萄糖指数(OGI)的新方法，即氧气消耗与葡萄糖消耗的比率。健康对照组的OGI是双侧对称的，而癫痫患者发作间期OGI在癫痫发作病灶的同侧增加。左图为18例健康对照组的平均图像，以及右/左颞叶癫痫(RTLE/LTLE)的代表性患者。红圈表示已知病变。                                 

High-resolution oxidative metabolism in the awake and anesthetized mouse brain by relaxometry-based calibrated fMRI

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2.Zhang M, Qin QK, Zhang SN, Liu W, Meng HP, Xu MY, Huang XY, Lin XZ, Lin M, Herman P et al: Aerobic glycolysis imaging of epileptic foci during the inter-ictal period. Ebiomedicine 2022, 79.

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