Research interests in the Xu group include deciphering the signaling pathways of G-protein coupled receptors (GPCRs) in human cells, with an emphasis on GPCR signaling in developmental biology. My lab will employ the cutting-edge technologies in GPCR structural biology and leverage extensive collaborations with other research groups to explore the critical involvement of GPCRs in embryogenesis and tissue homeostasis regulation, and the direct relevance of dysregulation of GPCR signaling to numerous human diseases.