Research

Research

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1.     

Yu, J., Gimenez, L. E., Hernandez, C. C., Wu, Y., Wein, A. H., Han, G. W., Mcclary, K., Mittal, S. R., Burdsall, K., Stauch, B., Wu, L., Stevens, S. N., Peisley, A. Williams, S. Y., Chen, V., Millhauser, G. L., Zhao, S., Cone, R. D., Stevens, R. C. (2020). Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding. Science, 368, 428–433.

2.     

Lin, X., Li, M., Wang, N., Wu, Y., Luo, Z., Guo, S., Han, G.-W., Li, S., Yue, Y., Wei, X., Xie, X., Chen, Y., Zhao, S., Wu, J., Lei, M. and Xu, F. (2020). Structural basis of ligand recognition and self-activation of orphan GPR52. Nature, 1–6.

3.     

Hua, T., Li, X., Wu, L., Iliopoulos-Tsoutsouvas, C., Wang, Y., Wu, M., Shen, L., Johnston, C. A.,Nikas, S. P., Song, F., Song, X., Yuan, S.,Sun, Q., Wu, Y., Jiang, S., Grim, T. W., Benchama, O., Stahl, E. L., Zvonok, N., Zhao, S., Bohn, L. M., Makriyannis, A. and Liu, Z. J. (2020). Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures. Cell, 180(4), 655-665.e18.

4.     

Zhang, B., Zhao, S., Yang, D., Wu, Y., Xin, Y., Cao, H., Huang, X. P., Cai, X., Sun, W., Ye, N., Xu, Y., Peng, Y., Zhao, S., Liu, Z. J., Zhong, G., Wang, M. W. and Shui, W. (2020). A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts. ACS Central Science, 6, 213–225.

5.     

Wu, F., Yang, L., Hang, K., Laursen, M., Wu, L., Han, G. W., Ren, Q., Roed, N. K., Lin, G., Hanson, M. A., Jiang, H., Wang, M. Reedtz-runge, S., Song, G., Stevens, R. C. (2020). Full-length human GLP-1 receptor structure without orthosteric ligands. Nature Communications, 11, 1–10.

6.     

Li, S. and Shui, W. (2020). Systematic mapping of protein–metabolite interactions with mass spectrometry-based techniques. Current Opinion in Biotechnology, 64, 24–31.

7.     

Wang, J., Wu, M., Wu, L., Xu, Y., Li, F., Wu, Y., Popv, P., Wang, L., Bai, F., Zhao, S., Liu, Z. J. and Hua, T. (2020). The structural study of mutation-induced inactivation of human muscarinic receptor M4. IUCrJ, 7, 294–305.

8.     

Fan, L., Tan, L., Chen, Z., Qi, J., Nie, F., Luo, Z., Cheng, J. and Wang, S. (2020). Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands. Nature Communications, 11(1), 1074.

9.     

Qian, J., Wang, Y., Pan, J., Chen, Z., Wang, C., Chen, J., Wu, Z. and Yangyue. (2020). Non-enzymatic glucose sensor based on ZnO–CeO2 whiskers. Materials Chemistry and Physics, 239, 122051.