Research

Research

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1.     

Li Z., Lu Y., Guo Y., Cao H., Wang Q., Shui W.,(2018). Comprehensive evaluation of untargeted metabolomics data processing software in feature detection, quantification and discriminating marker selection (vol 1029, pg 50, 2018). Analytica Chimica Acta, 1044.199.


2.     

Zhang X., Dong S., Xu F.,(2018). Structural and Druggability Landscape of Frizzled G Protein-Coupled Receptors. Trends in Biochemical Sciences, 43.1033-1046.


3.     

Tan L., Yan W., Mccorvy J.D., Cheng J.,(2018). Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential. Journal of Medicinal Chemistry, 61.9841-9878.


4.     

Gong W., Hu W., Xu L., Wu H., Wu S., Zhang H., Wang J., Jones G.W., Perrett S.,(2018). The C-terminal GGAP motif of Hsp70 mediates substrate recognition and stress response in yeast. The Journal of biological chemistry, 293.46):17663-17675.


5.     

Billings J.C.W., Thompson G.J., Pan W., Magnuson M.E., Medda A., Keilholz S.,(2018). Disentangling Multispectral Functional Connectivity With Wavelets. Frontiers in Neuroscience, 12.


6.     

Zhao H., Tian X., He L., Li Y., Pu W., Liu Q., Tang J., Wu J., Cheng X., Liu Y., Zhou Q., Tan Z., Bai F., Xu F., Smart N., Zhou B.,(2018). Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target. Cell Reports, 25.1241.


7.     

Thompson G.J.,(2018). Neural and metabolic basis of dynamic resting state fMRI. Neuroimage, 180.448-462.


8.     

Liu D., Wei Y., Liu X., Zhou Y., Jiang L., Yin J., Wang F., Hu Y., Urs A.N.N., Liu Y., Ang E.L., Zhao S., Zhao H., Zhang Y.,(2018). Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole. Nature Communications, 9.


9.     

Zhang S., Ding K., Shen Q., Zhao S., Liu J.,(2018). Filamentation of asparagine synthetase in Saccharomyces cerevisiae. PLoS Genetics, 14.


10.     

Qu L., Jiang Y., Cheng C., Wu D., Meng B., Chen Z., Zhu Y., Shaw N., Ouyang S., Liu Z.,(2018). Crystal Structure of ATP-Bound Human ABCF1 Demonstrates a Unique Conformation of ABC Proteins. Structure, 26.9):1259-1265.


11.     

Miao C., Yang Y., Li S., Guo Y., Shui W., Cao Q.,(2018). Discrimination and quantification of homologous keratins from goat and sheep with dual protease digestion and PRM assays. Journal of Proteomics, 186.38-46.


12.     

Wang Y.S., Zhang B., Zhu J., Yang C.L., Guo Y., Liu C.L., Liu F., Huang H., Zhao S., Liang Y., Jiao R.H., Tan R.X., Ge H.M.,(2018). Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. Journal of the American Chemical Society, 140.10909-10914.


13.     

Chan H.C.S., Wang J., Palczewski K., Filipek S., Vogel H., Liu Z., Yuan S.,(2018). Exploring a new ligand binding site of G proteincoupled receptors. Chemical Science, 9.


14.     

Zhou J., Zhao S., Dunker A.K.,(2018). Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation. Journal of Molecular Biology, 430.2342-2359.


15.     

Zhao M., Cheng J., Guo B., Duan J., Che C.,(2018). Momilactone and Related Diterpenoids as Potential Agricultural Chemicals. Journal of Agricultural and Food Chemistry, 66.7859-7872.


16.     

Pu M., Xu Z., Peng Y., Hou Y., Liu D., Wang Y., Liu H., Song G., Liu Z.,(2018). Protein crystal quality oriented disulfide bond engineering. Protein & Cell, 9.659-663.


17.     

Vysotski E., Markova S., Natashin P., Stepanyuk G., Lee J., Malikova N., Liu Z.,(2018). Hydrogen bond network near OH group of 6-(p-hydroxyphenyl) substituent of coelenterazine determines the bioluminescence spectra differences among hydromedusan calcium-regulated photoproteins. 8.435-436.


18.     

Popov P., Peng Y., Shen L., Stevens R.C., Cherezov V., Liu Z., Katritch V.,(2018). Computational design of thermostabilizing point mutations for G protein-coupled receptors. ELife, 7.


19.     

Cao C., Tan Q., Xu C., He L., Yang L., Zhou Y., Zhou Y., Qiao A., Lu M., Yi C., Han G.W., Wang X., Li X., Yang H., Rao Z., Jiang H., Zhao Y., Liu J., Stevens R.C., Zhao Q., Zhang X.C., Wu B.,(2018). Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nature Structural & Molecular Biology, 25.488.


20.     

Cheng X., Wang R., Shen Q.,(2018). Cryo-ET bridges the gap between cell biology and structural biophysics. Chinese Physics B, 27.6):66803.


21.     

Yang S.Wu Y., Xu T.H., de Waal P.W., He Y., Pu M.Chen Y., Debruine Z.J., Zhang B., Zaidi S.A., Popov P., Guo Y., Han G.W., Lu Y., Suino-Powell K., Dong S., Harikumar K.G., Miller L.J., Katritch V., Xu H.E., Shui W.Stevens R.C., Melcher K., Zhao S.Xu F.,(2018). Crystal structure of the Frizzled 4 receptor in a ligand-free state. Nature, 

22.     

Qiu, B., Xia, B., Zhou, Q., Lu, Y., He, M., Hasegawa, K., Ma, Z., Zhang, F., Gu, L., Mao, Q., Wang, F., Zhao, S., Gao, Z., and Liao, J. (2018). Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate. CELL RES 28, 644-654.

23.     

Huang, L., Tong, X., Wang, F., Luo, L., Jin, R., Fu, Y., Zhou, G., Li, D., Song, G., Liu, Y., and Zhu, F. (2018). Novel mutations in PATL2 cause female infertility with oocyte germinal vesicle arrest. HUM REPROD 33, 1183-1190.

24.     

Liu, X., Gao, Z., Wu, Y., Stevens, R.C., Jacobson, K.A., and Zhao, S. (2018). Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y(1)and P2Y(12) receptors. SCI REP-UK 8.

25.     

Vass, M., Kooistra, A.J., Yang, D., Stevens, R.C., Wang, M., and de Graaf, C. (2018). Chemical Diversity in the G Protein-Coupled Receptor Superfamily. TRENDS PHARMACOL SCI 39, 494-512.

26.     

Xiao, W., Duan, X., Lin, Y., Cao, Q., Li, S., Guo, Y., Gan, Y., Qi, X., Zhou, Y., Guo, L., Qin, P., Wang, Q., and Shui, W. (2018). Distinct Proteome Remodeling of Industrial Saccharomyces cerevisiae in Response to Prolonged Thermal Stress or Transient Heat Shock. J PROTEOME RES 17, 1812-1825.

27.     

Yang, Z., Han, S., Keller, M., Kaiser, A., Bender, B.J., Bosse, M., Burkert, K., Koegler, L.M., Wifling, D., Bernhardt, G., Plank, N., Littmann, T., Schmidt, P., Yi, C., Li, B., Ye, S., Zhang, R., Xu, B., Larhammar, D., Stevens, R.C., Huster, D., Meiler, J., Zhao, Q., Beck-Sickinger, A.G., Buschauer, A., and Wu, B. (2018). Structural basis of ligand binding modes at the neuropeptide Y Y-1 receptor. NATURE 556, 520.

28.     

Shang, W., Jiang, Y., Boettcher, M., Ding, K., Mollenauer, M., Liu, Z., Wen, X., Liu, C., Hao, P., Zhao, S., McManus, M.T., Wei, L., Weiss, A., and Wang, H. (2018). Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation. P NATL ACAD SCI USA 115, E4051-E4060.

29.     

Li, Z., Li, Y., Chen, W., Cao, Q., Guo, Y., Wan, N., Jiang, X., Tang, Y.J., Wang, Q., and Shui, W. (2018). Integrating MS1 and MS2 Scans in High-Resolution Parallel Reaction Monitoring Assays for Targeted Metabolite Quantification and Dynamic C-13-Labeling Metabolism Analysis (vol 89, pg 877, 2017). ANAL CHEM 90, 5509.

30.     

Zhang, W., Sun, S., Yang, L., Lu, C., He, Y., Zhang, C., Cai, M., Yao, Y., Zhang, F., and Zhuang, X. (2018). Polymer nanosheets derived porous carbon nanosheets as high efficient electrocatalysts for oxygen reduction reaction. J COLLOID INTERF SCI 516, 9-15.

31.     

Qin, S., Meng, M., Yang, D., Bai, W., Lu, Y., Peng, Y., Song, G., Wu, Y., Zhou, Q., Zhao, S., Huang, X., McCorvy, J.D., Cai, X., Dai, A., Roth, B.L., Hanson, M.A., Liu, Z., Wang, M., Stevens, R.C., and Shui, W. (2018). High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. CHEM SCI 9, 3192-3199.

32.     

Johnson, F.K., Delpech, J., Thompson, G.J., Wei, L., Hao, J., Herman, P., Hyder, F., and Kaffman, A. (2018). Amygdala hyper-connectivity in a mouse model of unpredictable early life stress. TRANSL PSYCHIAT 8.

33.     

Peng, Y., McCorvy, J.D., Harpsoe, K., Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajsen, L.F., Huang, X., Wu, Y., Shen, L., Bjorn-Yoshimoto, W.E., Ding, K., Wacker, D., Han, G.W., Cheng, J., Katritch, V., Jensen, A.A., Hanson, M.A., Zhao, S., Gloriam, D.E., Roth, B.L., Stevens, R.C., and Liu, Z. (2018). 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. CELL 172, 719-730.

34.     

Yan, X., Shi, Q., Bracher, A., Milicic, G., Singh, A.K., Hartl, F.U., and Hayer-Hartl, M. (2018). GroEL Ring Separation and Exchange in the Chaperonin Reaction. CELL 172, 605.

35.     

Ye, M., Yang, J., Tian, C., Zhu, Q., Yin, L., Jiang, S., Yang, M., and Shu, Y. (2018). Differential roles of Na(V)1.2 and Na(V)1.6 in regulating neuronal excitability at febrile temperature and distinct contributions to febrile seizures. SCI REP-UK 8.

36.     

Zhang, H., Qiao, A., Yang, L., Van Eps, N., Frederiksen, K.S., Yang, D., Dai, A., Cai, X., Zhang, H., Yi, C., Cao, C., He, L., Yang, H., Lau, J., Ernst, O.P., Hanson, M.A., Stevens, R.C., Wang, M., Reedtz-Runge, S., Jiang, H., Zhao, Q., and Wu, B. (2018). Structure of the glucagon receptor in complex with a glucagon analogue. NATURE 553, 106.

37.     

Qiu, X., Huang, Y., Wu, D., Mao, F., Zhu, J., Yan, W., Luo, H., and Li, J. (2018). Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation. BIOORGAN MED CHEM 26, 119-133.

38.     

Yang X., Wang R., Wang X., Cai G., Qian Y., Feng S., Tan F., Chen K., Tang K., Huang X., Jing N., Qiao Y.,(2018). TGFβ signaling hyperactivation-induced tumorigenicity during the derivation of neural progenitors from mouse ESCs. Journal of Molecular Cell Biology, 10.3):216-228.