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Year 2015

1.  Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE. Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22.

2.  Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Chrencik JE, Roth CB, Terakado M, Kurata H, Omi R, Kihara Y, Warshaviak D, Nakade S, Asmar-Rovira G, Mileni M, Mizuno H, Griffith MT, Rodgers C, Han GW, Velasquez J, Chun J, Stevens RC, Hanson MA. Cell. 2015 Jun 18;161(7):1633-43. doi: 10.1016/j.cell.2015.06.002.

3.  Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, Yefanov OM, White TA, Wang C, Ishchenko A, Tirupula KC, Desnoyer R, Coe J, Conrad CE, Fromme P, Stevens RC, Katritch V, Karnik SS, Cherezov V. Cell. 2015 May 7;161(4):833-44. doi: 10.1016/j.cell.2015.04.011. Epub 2015 Apr 23.

4.  Two disparate ligand-binding sites in the human P2Y1 receptor. Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, Stevens RC, Jacobson KA, Zhao Q, Wu B. Nature. 2015 Apr 16;520(7547):317-21. doi: 10.1038/nature14287. Epub 2015 Mar 30.

5.  New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16. Ni X, Ru H, Ma F, Zhao L, Shaw N, Feng Y, Ding W, Gong W, Wang Q, Ouyang S, Cheng G, Liu ZJ. J Mol Cell Biol. 2015 Aug 5. pii: mjv053. [Epub ahead of print]

6.  Conformational states of the full-length glucagon receptor. Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H. Nat Commun. 2015 Jul 31;6:7859. doi: 10.1038/ncomms8859.

7.  A novel periplasmic protein (Slr0280) tunes photomixotrophic growth of the cyanobacterium, Synechocystis sp. PCC 6803. Dong LL, Li QD, Wu D, Sun YF, Zhou M, Zhao KH. Gene. 2015 Sep 11. pii: S0378-1119(15)01095-1. doi: 10.1016/j.gene.2015.09.015. [Epub ahead of print]

8.  The importance of ligands for G protein-coupled receptor stability. Zhang X, Stevens RC, Xu F. Trends Biochem Sci. 2015 Feb;40(2):79-87. doi: 10.1016/j.tibs.2014.12.005. Epub 2015 Jan 15.

Year 2014

1. Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q., (2014) Structure of the human P2Y12 receptor in complex with an antithrombotic drug, Nature, 509(7498):115-8.

2. Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q., (2014) Agonist-bound structure of the human P2Y12 receptor, Nature, 509(7498):119-22.

3. Zhao, L., Hua, t., Crowley, C., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Hung, L., Huang, W., Liu, L., Ye, K., OuYang, S*, Cheng, G*, and Liu, Z. J*, (2014) Structural analysis of asparaginylendopeptidase reveals the activation mechanism and a reversible intermediate maturation stage, Cell Res, 24(3):344-58

4. Natashin PV, Ding W, Eremeeva EV, Markova SV, Lee J, Vysotski ES, Liu ZJ., (2014) Structures of the Ca2+-regulated photoproteinobelin Y138F mutant before and after bioluminescence support the catalytic function of a water molecule in the reaction. ActaCryst. D, 70(Pt3):720-32.

5. Jiao L, Ouyang S, Shaw N, Song G, Feng Y, Niu F, Qiu W, Zhu H, Hung LW, Zuo X, Shtykova E, Zhu P, Dong YH, Xu R*, Liu ZJ*. (2014) Mechanism of the Rpn13-induced activation of Uch37, Protein Cell, 10.1007/s13238-014-0046-z.

6. Natashin PV, Markova SV, Lee J, Vysotski ES, Liu ZJ (2014) Crystal structures of the F88Y obelin mutant before and after bioluminescence provide molecular insight into spectral tuning among hydromedusan photoproteins. FEBS J. 281(5):1432-45.

7. Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, Ting J (2014) NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING, Immunity, 40(3): 329-341.

8. Song, G., Cheng, C., Wang, Li, Y., L., Ding, Shaw, N., Xiao, Z*, and Liu, Z. J*, (2014) Crystal structure of the N-terminal methyltransferase-like Proteins, doi: 10.1002/prot.24443.

9. J. Gu, Y. Feng, X. Feng, C. Sun, L. Lei, W. Ding, F. Niu, L. Jiao, M. Yang, Y. Li, X. Liu, J. Song, Z. Cui, D. Han, C. Du, Y. Yang, S. Ouyang, Z. J. Liu, W. Han, (2014) Structural and Biochemical Characterization Reveals LysGH15 as an Unprecedented “EF-Hand-Like” Calcium-Binding Phage Lysin, PLOS Pathogens, DOI: 10.1371/journal.ppat.1004109