To image the human body at the molecular, cellular, and human scale and to build an atomic resolution model of the integrated human body is the iHuman Institute research mission. We understand this is an incredibly ambitious research plan and the methods to integrate the data do not exist today.We believe this goal is the future of biomedical research, and that most of the technologies exist today to collect the individual types of data on the time and space scales, but significant effort is needed to achieve meaningful data integration across these varied disciplines.We believe our research at the iHuman Institute will lead the way in integrating human-related scientific data at the different spatial and temporal scales to improve our ability to diagnose and treat human disease.
More than 800 G-Protein Coupled Receptors (GPCRs) constitute the largest protein family in the human genome. Along with rich set of interacting partners and pathways, these proteins play extremely versatile roles in human physiology/pathophysiology, and are drug targets with crucial clinical significance.
Molecular tree of GPCR family
Biological functions of GPCRs
Through a highly efficient high-throughput pipeline, iHuman’s 826 Project aims to establish the first complete library of the whole GPCR family worldwide, which will greatly accelerate the nextstage of studies in all fields of GPCR science.