Teacher

Dong Wu Research Associate Professor

Publishtimes:2017-08-23Views:15设置


InstituteiHuman Institute
Research AreaStructural Biology & Biophysics
Contactwudong@shanghaitech.edu.cn
Wu Dong
hat26Biography

2013/11-NOW   iHuman institute, Shanghaitech university


2012/1-2013/11 National Laboratory of Biomacromolecules, Institute of biophysics, CAS, Associate Professor

2010/1-2011/12 National Laboratory of Biomacromolecules, Institute of biophysics, CAS, Assistant Professor

2007/7-2009/12 National Laboratory of Biomacromolecules, Institute of biophysics, CAS, Post-doc

2006/3-2007/6   Wuhan Botanical Garden, CAS, Assistant Professor

2004/2-2005/2   Munich University and Max-Plank Institute of Biochemistry, German, Visiting Scientist

2001/09-2006/1  Huazhong University of Science and Technology, P.R.China

School of life science and Technology    Doctor

1998/09-2001/07  Huazhong University of Science and Technology, P.R.China

School of life science and Technology    Master

1994/09-1998/07  Henan normal university, Bio-technique,  Bachelor

helix2Research Interests
Structural and functional analysis of human disease related proteins


Identifying mechanism of enzyme & drug targets by biophysics methods

bookSelected Publications

1.Guohui Pan, Xiaoqin Gao, Keqiang Fan, Junlin Liu, Bing Meng, Jinmin Gao, Bin Wang, Chaobo Zhang, Hui Han, Guomin Ai, Yihua Chen, Dong Wu*, Zhi-Jie Liu*, Keqian Yang* (2016) Structure and Function of a C–C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis. ACS Chem. Biol.,DOI: 10.1021/acschembio.6b00621
2. Lv X, Liu J, Shi Q, Tan Q, Wu D, Skinner J, Walker A, Katritch V, Liu ZJ, Stevens R (2016) In vitro expression and analysis of the 826 human G protein-coupled receptors. Protein Cell, 7(5):325-37.
3.Dong LL, Li QD, Wu D, Sun YF, Zhou M, Zhao KH. (2016). “A novelperiplasmic protein (Slr0280) tunes photomixotrophic growth of the cyanobacterium, Synechocystis sp. PCC 6803.” Gene. 575(2):313-320.
4.Guo P, Zhao Z, Haak J, Wang S, Wu D, Meng B, Weitao T. (2014). “Common mechanisms of DNA translocation motors in bacteria and viruses using one-way revolution mechanism without rotation.” Biotechnol Adv. 32(4):853-872.
5.Liu ZJ, Chen L, Wu D, Ding W, Zhang H, Zhou W, Fu ZQ, Wang BC. (2011). “A multi-dataset data-collection strategy produces better diffraction data.” Acta Crystallogr A. 67 (6):544-549.
6.Meng B, Wu D*, Gu J, Ouyang S, Ding W, Liu ZJ. (2014). Structural and functional analyses of human tryptophan 2,3-dioxygenase. Proteins. 82(11):3210-3216.
7.Wu, D#., Li, Y., Song, GJ., Cheng,CY., Zhang R G., Joachimiak, A., Shaw, N.*, & Liu, Z. J*.(2009). “Structural basis for the inhibition of human MTHFS by N10-substituted folate analogues.” Cancer Research. 69(18): 7294-7301.
8.Wu, D#., Li, Y., Song, GJ, Zhang, D, Shaw, N., & Liu, Z. J*. (2009). “Crystal structure of human esterase D: a potential genetic marker of retinoblastoma.” FASEB J. 23(5): 1441-1446.
9.Hua T#, Wu D#, Ding W, Wang J, Shaw N, Liu ZJ. (2012) “Studies of Human 2,4-Dienoyl CoA Reductase Shed New Light on Peroxisomal β-Oxidation of Unsaturated Fatty Acids. ” J. Biol. Chem. 287(34): 28956-28965.


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