Teacher

Yunbo Qiao Research Assistant Professor

Publishtimes:2017-08-23Views:14设置


InstituteiHuman Institute
Research AreaEpigenetic regulation and stem cells
Contactqiaoyb@shanghaitech.edu.cn
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hat26Biography


2016-present

Research Assistant Professor, iHuman Institute, ShanghaiTech University

2012-2016

Postdoc, State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences

2006-2012

Ph.D. State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences

2002-2006

B.S. Wuhan University, China

helix2Research Interests
I always focus on studying the functional relationship between epigenetic regulations and biological processes. Currently, I am interested in screening chemicals and epigenetic factors involved in immune suppression for potential cancer therapy. Our goal is to understand the mechanism underlying epigenetic regulation and cancer progression.
bookSelected Publications
  • Xiongjun Wang#, YunboQiao#, Minzhe Xiao, Lingbo Wang, Jun Chen, Wenjian Lv, Jinsong Li, Naihe Jing#, Y. Eugene Chin1#. Opposite roles of acetylation and serine-phosphorylation in modulating LIFR self-renewal growth signaling in mESCs. Cell Reports. 2017 (Co-first author)

  • Yunbo Qiao, Xianfa Yang, and Naihe Jing. Epigenetic regulation of early neural fate commitment. Cellular and Molecular Life Sciences. 73: 1399. 2016

  • Yunbo Qiao#, Ran Wang#, Xianfa Yang, Ke Tang, and Naihe Jing*. Dual Roles of Histone H3 Lysine 9 Acetylation in Human Embryonic Stem Cell Pluripotency and Neural Differentiation. J Biol Chem. 290(4): p. 2508-20. 2015

  • Yunbo Qiao#, Xiongjun Wang#, Ran Wang, Yuanyuan Li, Fang Yu, Xianfa Yang, Lu Song,Guoliang Xu, Y. Eugene Chin*, and Naihe Jing*. AF9 Promotes hESC Neural Differentiation through Recruiting TET2 to Neurodevelopmental Gene Loci for Methylcytosine Hydroxylation. Cell Discovery. 1, 2015.

  • Yunbo Qiao, Yue Zhu, Nengyin Sheng, Jun Chen, Ran Tao,Qingqing Zhu, Ting Zhang, Cheng Qian, and Naihe Jing*. AP2γ regulates neural and epidermal development downstream of the BMP pathway at early stages of ectodermal patterning. Cell Research. 2012; 22(11):1546-61.

  • Yunbo Qiao, Naihe Jing. Human Neural Development and Human Embryonic Stem Cell Neural Differentiation. Stem Cells: Basics and Clinical Translation (eBook, chapter 8). DOI 10.1007/978-94-017-7273-0

  • Ke Tang, Guangdun Peng, Yunbo Qiao, Lu Song,and Naihe Jing*. Intrinsic regulations in neural fate commitment. Dev Growth Differ. 57, 109–120, 2015.

  • Qingqing Zhu, Lu Song, Guangdun Peng, Na Sun, Jun Chen, Ting Zhang, Nengyin Sheng, Wei Tang, Cheng Qian, Yunbo Qiao, Ke Tang, Jing-Dong J Han, Jinsong Li, Naihe Jing*. The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways. eLife 2014;10.7554.02224.

  • Pingyu Liu, Xiaoyang Dou, Chang Liu, Can Xing, Guangdun Peng, Jun Chen, Fang Yu, Yunbo Qiao, Fuming Li, Lu Song, Chunmei Yue, Jing-Dong J. Han, Ke Tang, Naihe Jing*. Histone deacetylation promotes mouse neural induction by restricting Nodal-dependent mesendoderm fate. Nature communications 6,

  • Ting Zhang, Qingqing Zhu, Zhihui Xie, Yongfeng Chen, Yunbo Qiao, Lingyu Li, and Naihe Jing*.The zinc finger transcription factor Ovol2 acts downstream of the bone morphogenetic protein pathway to regulate the cell fate decision between neuroectoderm and mesendoderm. J Biol Chem.288(9): p. 6166-77, 2013.


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