Yunbo Qiao Research Assistant Professor

InstituteiHuman Institute
Research AreaEpigenetic regulation and stem cells


Research Assistant Professor, iHuman Institute, ShanghaiTech University


Postdoc, State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences


Ph.D. State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences


B.S. Wuhan University, China

helix2Research Interests
I always focus on studying the functional relationship between epigenetic regulations and biological processes. Currently, I am interested in screening chemicals and epigenetic factors involved in immune suppression for potential cancer therapy. Our goal is to understand the mechanism underlying epigenetic regulation and cancer progression.
bookSelected Publications
  • Xiongjun Wang#, YunboQiao#, Minzhe Xiao, Lingbo Wang, Jun Chen, Wenjian Lv, Jinsong Li, Naihe Jing#, Y. Eugene Chin1#. Opposite roles of acetylation and serine-phosphorylation in modulating LIFR self-renewal growth signaling in mESCs. Cell Reports. 2017 (Co-first author)

  • Yunbo Qiao, Xianfa Yang, and Naihe Jing. Epigenetic regulation of early neural fate commitment. Cellular and Molecular Life Sciences. 73: 1399. 2016

  • Yunbo Qiao#, Ran Wang#, Xianfa Yang, Ke Tang, and Naihe Jing*. Dual Roles of Histone H3 Lysine 9 Acetylation in Human Embryonic Stem Cell Pluripotency and Neural Differentiation. J Biol Chem. 290(4): p. 2508-20. 2015

  • Yunbo Qiao#, Xiongjun Wang#, Ran Wang, Yuanyuan Li, Fang Yu, Xianfa Yang, Lu Song,Guoliang Xu, Y. Eugene Chin*, and Naihe Jing*. AF9 Promotes hESC Neural Differentiation through Recruiting TET2 to Neurodevelopmental Gene Loci for Methylcytosine Hydroxylation. Cell Discovery. 1, 2015.

  • Yunbo Qiao, Yue Zhu, Nengyin Sheng, Jun Chen, Ran Tao,Qingqing Zhu, Ting Zhang, Cheng Qian, and Naihe Jing*. AP2γ regulates neural and epidermal development downstream of the BMP pathway at early stages of ectodermal patterning. Cell Research. 2012; 22(11):1546-61.

  • Yunbo Qiao, Naihe Jing. Human Neural Development and Human Embryonic Stem Cell Neural Differentiation. Stem Cells: Basics and Clinical Translation (eBook, chapter 8). DOI 10.1007/978-94-017-7273-0

  • Ke Tang, Guangdun Peng, Yunbo Qiao, Lu Song,and Naihe Jing*. Intrinsic regulations in neural fate commitment. Dev Growth Differ. 57, 109–120, 2015.

  • Qingqing Zhu, Lu Song, Guangdun Peng, Na Sun, Jun Chen, Ting Zhang, Nengyin Sheng, Wei Tang, Cheng Qian, Yunbo Qiao, Ke Tang, Jing-Dong J Han, Jinsong Li, Naihe Jing*. The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways. eLife 2014;10.7554.02224.

  • Pingyu Liu, Xiaoyang Dou, Chang Liu, Can Xing, Guangdun Peng, Jun Chen, Fang Yu, Yunbo Qiao, Fuming Li, Lu Song, Chunmei Yue, Jing-Dong J. Han, Ke Tang, Naihe Jing*. Histone deacetylation promotes mouse neural induction by restricting Nodal-dependent mesendoderm fate. Nature communications 6,

  • Ting Zhang, Qingqing Zhu, Zhihui Xie, Yongfeng Chen, Yunbo Qiao, Lingyu Li, and Naihe Jing*.The zinc finger transcription factor Ovol2 acts downstream of the bone morphogenetic protein pathway to regulate the cell fate decision between neuroectoderm and mesendoderm. J Biol Chem.288(9): p. 6166-77, 2013.