Kurt Wüthrich Professor, 2002 Nobel Laureate in chemistry


tituteiHuman Institute
Research AreaMolecular Structural Biology

1957–62 University of Bern, Switzerland: Lizentiat in chemistry, physics and mathematics.
1962–64 University of Basel, Switzerland: Ph.D. in chemistry (Prof. S. Fallab); Eidgen?ssisches Turnund Sportlehrerdiplom.
1964–65 University of Basel, Switzerland: Postdoctoral training (Prof. S. Fallab).
1965–67 University of California, Berkeley, CA, USA : Postdoctoral training (Prof. R.E. Connick).
1967–69 Bell Telephone Laboratories, Murray Hill, N.J., USA : Member Technical Staff, Biophysics Department (Dr. R.G. Shulman).
1969– ETH Zurich, Zurich, Switzerland: Privatdozent (70), Assistant Professor (72), Associate Professor (76), Professor of Biophysics (80); Chairman Biology Department (95–2000).
2001–04 The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Visiting Professor of Structural Biology.
2004– The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Professor of Structural Biology.
helix2Research Interests
Biology, structure and function of proteins and nucleic acids; development of nuclear magnetic resonance
(NMR) techniques for macromolecular structure determination in solution and for studies of intermolecular
interactions; applications in structural genomics, proteomics and biomedical research.
bookSelected Publications

1.Liu, J.J., Horst, R., Katritch, V., Stevens, R.C. and Wüthrich, K. (2012) Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. Science 335, 1106-1110.

2.Horst, R., Stanczak, P., Serrano, P. and Wüthrich, K. (2012) Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solublized membrane protein OmpX. J. Phys. Chem. B 116, 6775–6780.

3.Serrano, P., Pedrini, B., Mohanty, B., Geralt, M., Herrmann, T. and Wüthrich K. (2012) The J-UNIO protocol for automated protein structure determination by NMR in solution. J. Biomol. NMR 53, 341–354.

4.Stanczak, P., Zhang, Q., Horst, R., Serrano, P. and Wüthrich, K. (2012) Micro-coil NMR to monitor optimization of the reconstitution conditions for the integral membrane protein OmpW in detergent micelles. J. Biomol. NMR 54, 129–133.

5.Horst, R., Stanczak, P., Stevens, R.C. and Wüthrich, K. (2012) β2-adrenergic receptor solutions for structural biology analyzed with micro-scale NMR diffusion measurements. Angew. Chem. 52(1):331-335.